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Tuesday, September 07, 2010

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Neuromyelitis Optica/Devic�s Disease

Download the Neuromyelitis Optica/Devic�s Disease (Vol. 9, Issue 3) Neura Issue

The current issue of Neura features an overview of neuromyelitis optica (NMO), including its pathophysiology and treatment and current views on differentiating NMO from multiple sclerosis (MS). Other articles include an analysis of the association between traumatic brain injury and neurodegenerative disease, an overview of fluctuations in quality of life in Parkinson’s disease (PD), and a Highlights section that summarizes several articles published recently in the literature.

CME Neuromyelitis Optica/Devic�s Disease
Neuromyelitis optica (NMO) resembles multiple sclerosis (MS) in many ways, but recently developed diagnostic criteria for NMO can distinguish the 2 diseases with high sensitivity and specificity. NMO is characterized by optic neuritis and myelitis and usually exhibits a relapsing course. This article reviews recent literature about the pathophysiology and treatment of NMO. The diagnostic criteria of NMO, as well as its differentiation from MS, are also addressed.

Sports Brain Injuries and Neurodegenerative Disease
Concussions and other forms of traumatic brain injury (TBI) are common occurrences in sports players. While the association between TBI and later-onset neurodegenerative disease has not been proven, recent research has suggested that the connection is strong. This article reviews the research surrounding brain injury-caused neurodegenerative diseases. Ongoing investigations with large populations of former sports players are also addressed.

Quality of Life in Parkinson�s Disease
There is a growing awareness of the influence of nonmotor symptoms (particularly depression) on the quality of life of people with PD. This article addresses the latest research into quality of life, including its measurement and its fluctuations. Also addressed are the effects of pharmacologic and nonpharmacologic PD treatments on quality of life.

Highlights From the Literature
Highlights from recent articles addressing biomarkers and disease course prediction include: imaging and cerebrospinal fluid (CSF) predictors of the conversion of radiologically isolated syndrome to MS, imaging predictors of the conversion of clinically isolated syndrome (CIS) to MS, and an online-only summary on CSF biomarkers for incipient Alzheimer�s disease (AD).

Patient Tear-Out: Maintaining a Good Quality of Life While Living With PD
Neura provides a summary to patients about ways to improve quality of life while living with Parkinson�s disease. These issues include taking an active role in medical care, starting an exercise regimen, eating a nutritious diet, maintaining a positive attitude, considering therapy or counseling, and joining a support group.

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