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Friday, September 10, 2010
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Pharmacogenomic Analysis in Multiple Sclerosis
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Hot Topic: Pharmacogenomic Analysis in Multiple Sclerosis
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References
References
1. PRISMS (Prevention of Relapses and Disability by Interferon beta-1a Subcutaneously in Multiple Sclerosis) Study Group. Randomised double-blind placebo-controlled study of interferon beta-1a in relapsing/remitting multiple sclerosis.
Lancet
. 1998;352:1498-1504. [
PubMed
]
2. Coyle PK, Hartung HP. Use of interferon beta in multiple sclerosis: rationale for early treatment and evidence for dose- and frequency-dependent effects on clinical response.
Mult Scler
. 2002;8:2-9. [
PubMed
]
3. O’Doherty C, Villoslada P, Vandenbroeck K. Pharmacogenomics of Type I interferon therapy: a survey of response-modifying genes.
Cytokine Growth Factor Rev
. 2007;18:211-222. [
PubMed
]
4. Goldstein DB, Tate SK, Sisodiya SM. Pharmacogenetics goes genomic.
Nat Rev Genet
. 2003;4:937-947. [
PubMed
]
5. van Baarsen LGM, Vosslamber S, Tijssen M, ogenomics of therapy in multiple sclerosis: baseline IFN signature determines pharmacological differences between patients.
PLoS ONE
. 2008;3:e1927(1-9). [
PubMed
]
6. Singh MK, Scott TF, LaFramboise WA, et al. Gene expression changes in peripheral blood mononuclear cells from multiple sclerosis patients undergoing b-interferon therapy.
J Neurol Sci
. 2007;258:52-59. [
PubMed
]
7. Goertsches R, Zettl UK. MS therapy research applying genome-wide RNA profiling of peripheral blood.
Int MS J
. 2007;14:98-107. [
PubMed
]
8. Byun E, Caillier SJ, Montalban X, et al. Genome-wide pharmacogenomic analysis of the response to interferon beta therapy in multiple sclerosis.
Arch Neurol
. 2008;65;337-344. [
PubMed
]
9. Fernald GH, Knott S, Pachner A, et al. Genome-wide network analysis reveals the global properties of IFN-b immediate transcriptional effects in humans.
J Immunol
. 2007;178:5076-5085. [
PubMed
]
10. Grossman I, Avidan N, Singer C, et al. Pharmacogenetics of glatiramer acetate therapy for multiple sclerosis reveals drug-response markers.
Pharmacogenet Genomics
. 2007;17;657-666. [
PubMed
]
11. Garren H, Robinson WH, Krasulova E, et al. Phase 2 trial of a DNA vaccine encoding myelin basic protein for multiple sclerosis.
Ann Neurol
. 2008;63:611-620. [
PubMed
]
12. Bar-Or A, Vollmer T, Antel J, et al. Induction of antigen-specific tolerance in multiple sclerosis after immunization with DNA encoding myelin basic protein in a randomized, placebo-controlled phase 1/2 trial.
Arch Neurol
. 2007;64:1407-1415. [
PubMed
]
13. Auman JT, McLeod HL. Cancer pharmacogenomics: DNA genotyping and gene expression profiling to identify molecular determinants of chemosensitivity.
Drug Metab Rev
. 2008;40:303-315. [
PubMed
]
14. Van Schaik RHN. CYP450 pharmacogenetics for personalizing cancer therapy.
Drug Resist Updat
. 2008;11:77-98. [
PubMed
]
15. Brugts JJ, Jan Danser AH, de Maat MPM, et al. Pharmacogenetics of ACE inhibition in stable coronary artery disease: steps toward tailored drug therapy.
Curr Opin Cardiol
. 2008;23:296-301. [
PubMed
]
16. Lee C, Morton CC. Structural genomic variation and personalized medicine.
N Engl J Med
. 2008;358:740-741. [
PubMed
]
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